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Investigating Data-Driven Climate-Adaptive Optimization of P. vivax Malaria Interventions in Seoul, the Republic of Korea

2025-12-15 epidemiology Title + abstract only
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Plasmodium vivax malaria control requires addressing unique challenges such as latent hypnozoite reservoirs, relapse-driven persistence, and strong climatic modulation of transmission. This study introduces a novel, integrative modeling-optimization framework that couples a relapse- and climate-aware transmission model with structural identifiablity analysis and metaheuristic optimization to design adaptive intervention strategies. Using surveillance data from Seoul, Korea, we calibrated key par...

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