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Yomix: An Interactive Tool for the Exploration of Low-Dimensional Embeddings in Omics Data

Perrin-Gilbert, N.; Amjad, N.; Fumeron, P.; Tulli, S.; Waterfall, J. J.

2025-12-10 bioinformatics
10.64898/2025.12.05.692343 bioRxiv
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SummaryIn the analysis of diverse omics data, a common and important preliminary step involves computing low-dimensional embeddings using techniques such as PCA, UMAP, t-SNE, or variational autoencoders. These embeddings provide a global overview of sample distributions and their relationships, often serving as the basis for formulating biological hypotheses. To facilitate rapid and intuitive exploration of such low-dimensional embeddings, we developed Yomix, an interactive omics-agnostic visualization and data exploration tool. Yomix enables users to flexibly define subsets of interest using a lasso selection tool, instantly compute their feature signatures, and compare their distributions. Yomix is a fast and efficient tool for interactive exploration of diverse omics datasets. Availability and ImplementationYomix and its documentation are publicly available at https://github.com/perrin-isir/yomix.

Published in Bioinformatics (predicted rank #1) · training set

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