Isolation of an antimicrobial resistant, biofilm forming, Klebsiella grimontii isolate from a re-usable water bottle.
Hubbard, A.; Reine, J.; Newire, E.; Wright, E.; Murphy, E.; Hutton, W.; Roberts, A.
Show abstract
A re-usable water bottle was swabbed as part of the citizen science project Swab and Send and a Klebsiella grimontii isolate was recovered on chromogenic agar and designated SS141. Whole genome sequencing of SS141 showed it has the potential to be a human pathogen as it contains the biosynthetic gene cluster for the potent cytotoxin, kleboxymycin, and genes for other virulence factors. The genome also contains blaOXY-6-4 and fosA which is likely to explain the observed resistance to ampicillin, amoxicillin and fosfomycin. We have also shown that SS141 is a potent biofilm former, providing a reasonable explanation for its ability to colonise a re-usable water bottle. With the increasing use of re-usable water bottles as an alternative to disposables, and a strong forecast for growth in this industry over the next decade, this study highlights the need for cleanliness comparable to other re-usable culinary items.
Matching journals
The top 7 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Transmissible antimicrobial resistance in Escherichia coli isolated from household drinking water in Ibadan, Nigeria 98%
- Occurrence, identification and antibiogram signatures of selected Enterobacteriaceae from Tsomo and Tyhume rivers in the Eastern Cape Province, Republic of South Africa. 97%
- First Indian report on Genome-wide Comparison of Multidrug-Resistant Escherichia coli from Blood Stream Infections 96%
Similar papers in this journal
- A novel hemA mutation is responsible for small colony variant phenotype in Escherichia coli. 96%
- Antibiotic resistance profiles and population structure of disease-associated Staphylococcus aureus infecting patients in Fort Portal Regional Referral Hospital, Western Uganda 95%
- A Functional Menadione Biosynthesis Pathway is Required for Capsule Production by Staphylococcus aureus. 94%
Similar papers in this journal
- Plasmid characterization in bacterial isolates of public health relevance in a tertiary healthcare facility in Kilimanjaro, Tanzania 97%
- A Longitudinal Study of Dominant E. coli Lineages and Antimicrobial Resistance in the Gut of Children Living in an Upper Middle-income Country 96%
- Genomic characterisation of an mcr-1 and mcr-3-producing Escherichia coli strain isolated from pigs in France 96%
Similar papers in this journal
- Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386 95%
- First hybrid complete genome of Aeromonas veronii reveals chromosome-mediated novel structural variant mcr-3.19 from human clinical specimen 94%
- Insight into the resistome and quorum sensing system of a divergent Acinetobacter pittii isolate from an untouched site of the Lechuguilla Cave 94%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.