Back

Evaluating Voice-Enabled Generative AI for Mental Health: Real-Time Performance and Safety Analyses

Ngo, N.; Sano, A.

2025-11-17 health informatics
10.1101/2025.11.14.25340246 medRxiv
Show abstract

This study investigates the integration of Voice AI into a locally hosted generative AI chatbot designed to function as a mental health assistant, with the goal of enabling intuitive, voice-based therapeutic interaction. Leveraging the Llama3.1 8B language model for privacy-preserving generation, the system combines Deepgrams Speech-to-Text API and OpenAIs Text-to-Speech API within a WebRTC-based framework to support low-latency, bi-directional communication. A custom pipeline facilitates real-time voice input and output, aiming to reduce barriers to engagement and foster a more natural conversational flow. Technical evaluation focuses on latency across short, long-form, and multi-turn dialogues, revealing response times within tolerable bounds for synchronous use. Prompt engineering and system prompt customization guide empathetic, context-aware responses in standard therapeutic scenarios, though limitations persist in handling edge cases. These findings suggest that locally hosted voice-enabled LLMs can support responsive, privacy-conscious mental health applications, with future work directed toward fine-tuning for high-risk interactions.

Matching journals

The top 3 journals account for 50% of the predicted probability mass.

1
Frontiers in Digital Health
20 papers in training set
Top 0.1%
28.0%
2
IEEE Journal of Biomedical and Health Informatics
34 papers in training set
Top 0.1%
12.5%
3
Journal of Medical Internet Research
85 papers in training set
Top 0.3%
12.5%
50% of probability mass above
4
Scientific Reports
3102 papers in training set
Top 17%
6.4%
5
JMIR Formative Research
32 papers in training set
Top 0.2%
4.9%
6
npj Digital Medicine
97 papers in training set
Top 0.9%
4.9%
7
PLOS ONE
4510 papers in training set
Top 42%
3.1%
8
PLOS Digital Health
91 papers in training set
Top 1%
2.1%
9
Frontiers in Psychiatry
83 papers in training set
Top 2%
2.1%
10
Philosophical Transactions of the Royal Society B
51 papers in training set
Top 3%
1.7%
11
JMIR mHealth and uHealth
10 papers in training set
Top 0.2%
1.5%
12
DIGITAL HEALTH
12 papers in training set
Top 0.4%
1.5%
13
Computers in Biology and Medicine
120 papers in training set
Top 3%
1.3%
14
Journal of the American Medical Informatics Association
61 papers in training set
Top 2%
1.0%
15
JMIR Public Health and Surveillance
45 papers in training set
Top 3%
0.8%
16
Journal of NeuroEngineering and Rehabilitation
28 papers in training set
Top 0.9%
0.8%
17
Journal of Biomedical Informatics
45 papers in training set
Top 1%
0.8%
18
Computer Methods and Programs in Biomedicine
27 papers in training set
Top 0.9%
0.8%
19
Biomedical Signal Processing and Control
18 papers in training set
Top 0.5%
0.7%
20
Brain Sciences
52 papers in training set
Top 2%
0.7%
21
Science
429 papers in training set
Top 20%
0.7%
22
iScience
1063 papers in training set
Top 37%
0.7%
23
Artificial Intelligence in Medicine
15 papers in training set
Top 0.9%
0.5%
24
Healthcare
16 papers in training set
Top 3%
0.5%