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Fatigue Symptoms Influence Effort-Based Decision-Making in Major Depressive Disorder
2025-10-31
psychiatry and clinical psychology
Title + abstract only
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BackgroundFatigue is a central symptom of major depressive disorder (MDD). Research in healthy individuals has shown that heightened feelings of fatigue are associated with a reduced willingness to exert effort. However, it remains unclear how fatigue affects effort-based decision-making in individuals with MDD. In this study, we explore how cognitive effort is traded for rewards in MDD and how feelings of fatigue and depressed mood symptoms influence this decision-making process. MethodsHealth...
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