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Should antigen-antibody rapid diagnostic tests be used to detect acute HIV infection? A systematic review and meta-analysis of diagnostic performance

2025-10-15 hiv aids Title + abstract only
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IntroductionPrompt HIV diagnosis is essential to enabling effective prevention and treatment, thereby interrupting transmission and sustain epidemic control. Strategies that could diagnose individuals during acute HIV infection (AHI), while leveraging standard systems that deliver same visit results, have potential to further enhance impact. Antibody-only (Ab) rapid diagnostic tests (RDTs), which are unable to detect AHI, remain the global standard, particularly in resource-limited settings. Ant...

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