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Antibacterial wound dressing enables reliable detection of uric acid in exudates.

lv, m.; Li, b.

2025-10-01 biochemistry
10.1101/2025.09.29.679342 bioRxiv
Show abstract

Through the successful grafting of epoxypropyl dimethyl dodecyl ammonium chloride (EDDAC) onto bacterial cellulose (BC) and multi-walled carbon nanotube (CNT) surfaces, a novel and stable antibacterial wound dressing (BC-CNTs-EDDAC) was fabricated. Compared with bare BC membranes, BC-EDDAC exhibited significantly enhanced antibacterial activity. Furthermore, a non-enzymatic uric acid sensor was constructed on the membrane surface via the self-assembly of AuNps, resulting in an antibacterial wound dressing with integrated UA-sensing capability. This design provides a new strategy for both promoting wound healing and real-time assessment of wound recovery status.

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