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Machine Learning Prediction of Pharmacogenetic Test Uptake Among Opioid-Prescribed Patients Using Electronic Health Records: A Retrospective Cohort Study
2025-09-28
health informatics
Title + abstract only
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BackgroundOpioids are a widely prescribed class of medication for pain management. However, they have variable efficacy and adverse effects among patients, due to complex interplay between biological and clinical factors. Pharmacogenetic (PGx) testing can be utilized to match patients genetic profiles to individualize opioid therapy, improving pain relief and reducing the risk of adverse effects. Despite its potential, PGx uptake--utilization of PGx testing--remains low due to a range of barrier...
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