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A minimal set of prompts to surface reasoning in digital health

Kulikovskikh, I.; Legovic, T.; Konovalov, S.; Kolsanov, A.; Smuc, T.

2025-09-24 health informatics
10.1101/2025.09.22.25336413 medRxiv
Show abstract

Digital health technologies can reduce workloads, enhance information retention, and minimize errors. However, when poorly integrated or misaligned with clinical practice, they often introduce new risks and allow unprocessed information to accumulate, amplifying existing challenges. The core problem is that reasoning often stays implicit and unstructured when translating needs into digital solutions. Without a shared way to make it explicit, critical inputs are missed, unprocessed information builds up, and reasoning faults spread through the system. We present a minimal, non-redundant set of eight plain-language prompts that spans the full reasoning process, guards against common reasoning faults, and provides a shared structure for aligning perspectives across stakeholders. We tested the set in a clinical case study on the initial management of septic shock, where the prompts helped to turn unstructured clinical reasoning into clear inputs for system design and workflow adjustments. To interpret its impact, we built a mathematical model that captures how unprocessed information changes over time. Compared with standard practice, the prompts reduced peak backlog by 20.3%, cumulative backlog by 22.2%, and improved recovery time from not reached to five time steps. We share an open-source code to model backlog dynamics, enabling easy adaptation to other clinical settings through parameter calibration. Author summaryIn digital health, the biggest challenge is not the technology but translation. What clinicians need and what developers create often do not align, resulting in tools that fail to meet the demands of real-world care. One key reason is that clinicians, developers, and administrators approach the same problem from different perspectives, and their reasoning is rarely made explicit or shared in a structured way. Our solution is a minimal yet complete set of plain-language prompts. These prompts make reasoning clear, bring experts onto the same page, and help to avoid common thinking traps like missing critical details, focusing too narrowly, or hesitating to act. In a clinical case of septic shock management, the prompts kept essential information visible, helped to set priorities in real time, and produced inputs directly relevant to patient care. By making critical details more visible, the prompt set enabled faster responses and led to fewer delays in treatment, while maintaining reliability. This set is compact enough for quick adoption and effective enough to bring together the perspectives of diverse expert groups, making it useful not only in hospitals but also in public health and other complex care settings.

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