Development, System Design, Safety, and Performance Metrics of a Conversational Agent for Reducing Depressive and Anxious Symptoms Based on a Large Language Model: The MHAI Study

2025-09-24 psychiatry and clinical psychology Title + abstract only

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BackgroundConversational agents based on large language models (LLMs) have shown moderate efficacy in reducing depressive and anxiety symptoms. However, most existing evaluations lack methodological transparency, rely on closed-source models, and show limited standardization in performance and safety assessment. ObjectiveWe have two study objectives: (1) to develop an LLM-based conversational agent through system design analysis and initial functionality testing, and (2) to evaluate its safety ...

Development, System Design, Safety, and Performance Metrics of a Conversational Agent for Reducing Depressive and Anxious Symptoms Based on a Large Language Model: The MHAI Study

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