Body surface gastric mapping parameters are associated with response to gastric peroral endoscopic myotomy for gastroparesis
Ayubi, H.; Varghese, C.; Tanne, M.; Schamberg, G.; Gulati, S.; Thrumurthy, S. G.; Patel, M.; Haji, A.; O'Grady, G.; Hayee, B.
Show abstract
MessageGastric per oral endoscopic myotomy (GPOEM) is a promising therapy for refractory gastroparesis, but patient selection remains challenging. We evaluated body surface gastric mapping (BSGM) phenotypes to predict treatment response. Patients were recruited at Kings College Hospital (Nov 2022-July 2025). BSGM comprised 30-min fasting, standardized nutrient drink with oatmeal bar (482 kcal), and 4-h postprandial recording. Success was defined as [≥]1 point reduction in Gastroparesis Cardinal Symptom Index or complete symptom resolution at follow-up. Overall, 53% responded, including all patients with dysrhythmic or continuous phenotypes. Higher gastric frequencies predicted non-response (p=0.03).
Matching journals
The top 3 journals account for 50% of the predicted probability mass.