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Pulmonary fibrosis after COVID-19 is characterized by airway abnormalities and elevated club cell secretory protein-16

2025-09-12 respiratory medicine Title + abstract only
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Prior studies testing biomarkers of residual lung abnormalities after COVID-19 are limited by sampling within the first year after acute COVID-19 illness and lack of external validation of findings. In three independent, international, racially and ethnically diverse prospective cohorts of survivors of moderate to critical COVID-19, we systematically tested 18 circulating biomarkers of inflammation, aging, endothelial activation, pulmonary epithelial function, fibrosis, and fibrinolysis. We foun...

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