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Placental Abnormalities of Malperfusion, Inflammation, and Meconium Precede Persistent Pulmonary Hypertension of the Newborn
2025-09-08
pediatrics
Title + abstract only
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BackgroundPersistent pulmonary hypertension of the newborn (PPHN) is a cause of neonatal hypoxic respiratory failure due to the failed transition of the pulmonary vasculature after birth. Mechanisms of disease are unknown, but we hypothesize they are directly related to insults in the intrauterine environment. The objective was to describe and compare placentas of PPHN infants to understand significant preceding factors from the maternal-fetal environment. MethodsWe conducted a case-control stu...
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