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Place-based disorder, social cohesion, and physical and mental health outcomes of LGBTQIA+ adults in the US

Tran, N. K.; Rehkopf, D. H.; Flohr, C.; Obedin-Maliver, J.; Flentje, A.; Lunn, M. R.

2025-09-07 epidemiology
10.1101/2025.09.04.25334946 medRxiv
Show abstract

Place-based disorder and social cohesion may influence LGBTQIA+ adults physical and mental health in meaningful ways given their heightened exposure to minority stress and discrimination. However, few studies have examined these associations. Using a sample of 3790 LGBTQIA+ adults in 786 counties from The Population Research in Identity and Disparities for Equality Study, we assessed associations of place-based disorder and social cohesion with depressive symptoms, perceived stress, and physical health using linear mixed models. We tested effect modification by gender modality and ethnoracial group. Residing in counties with higher social cohesion by 1-unit was associated with 1.06 lower points (95% CI -1.56, -0.56) for depressive symptoms, 1.60 lower points (95% CI -2.26, -0.94) for perceived stress, and 1.17 higher points (95% CI 0.43, 1.90) for physical health. Residence in counties with higher place-based disorder by 1-unit was only associated with 1.17 higher points (95% CI 0.32, 2.01) for perceived stress; no association was observed for depressive symptoms or physical health. Findings indicate that physical and social environments are important to the health of LGBTQIA+ individuals.

Published in AJE Advances: Research in Epidemiology · not in our set (fewer than 10 published preprints to learn from) · training set

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