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Prevalence and Factors Contributing to Dementia among Geriatric Patients attending Medical Outpatient Clinic at Mbeya Zonal Referral Hospital (MZRH); A Hospital Based Cross-Sectional Study.

Mahinyila, O.; Nyaborogo, K.

2025-08-08 psychiatry and clinical psychology
10.1101/2025.08.05.25333093 medRxiv
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BackgroundGlobally, one new case of Dementia develops in every three seconds. Patients with Cognitive Impairment usually have additional comorbidities which may accelerate progression towards a state of Cognitive Impairment. Furthermore, most suspected dementia patients visit primary physicians first instead of neurologists. This necessitates targeted screening of at-risk individuals for early intervention and prevention of Dementia. AimThis study aimed to assess the Prevalence and Factors Contributing to Dementia among Geriatric Patients attending Medical Outpatient Clinic at MZRH. MethodsA cross-sectional study was conducted in April, 2024 at MZRH, in 239 patients attending medical clinic, obtained by simple random sampling. The ethical approval was obtained from UDSM-MCHAS ethics committee, which presented approval letter to MZRH administration. Identification of Dementia for Elderly Africans (IDEA) cognitive screening questionnaire was used to assess Cognitive Impairment. From a range of 0-15, the scores were grouped into three categories; [≤] 7 indicating severe Cognitive Impairment (Dementia), 8-14 indicating mild to moderate Cognitive Impairment and 15 indicating normal cognitive function. Bivariate and Multivariate analysis was performed to assess factors associated with Cognitive Impairment. Results1 in 2 patients attending medical outpatient clinic had Cognitive Impairment. However, majority of patients had mild to moderate Cognitive Impairment (49.15%) as compared to severe Cognitive Impairment/Dementia (0.85%). Being [≥]65 years old (p=0.04), lack of formal education(p=0.02), and being male (p=0.001) were significantly associated with Cognitive Impairment. ConclusionA high proportion of Cognitive Impairment was observed among elderly medical outpatients, with majority of them in early stages of Cognitive Impairment. Age, educational level, and sex of the participants significantly affected Cognitive Impairment among study participants. Cognitive screening should form part of assessment for elderly patients attending medical clinic. There is a critical need to identify new interventions that can slow progression of Cognitive Impairment advancing to Dementia, particularly in patients with additional comorbidities.

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