Back

HIV Incidence Could Rise by 68% in 11 States if Ryan White Ends: A Simulation Study

Schnure, M.; Forster, R.; Jones, J. L.; Lesko, C. R.; Batey, D. S.; Butler, I.; Ward, D.; Musgrove, K.; Althoff, K. N.; Jain, M. K.; Gebo, K. A.; Dowdy, D.; Shah, M.; Kasaie, P.; Fojo, A. T.

2025-08-01 hiv aids
10.1101/2025.07.31.25332525 medRxiv
Show abstract

ObjectivesTo estimate the increase in HIV infections in 11 US states if Ryan White services are interrupted or ended. MethodsWe applied a population-level model of HIV transmission to 11 states. We represented the proportion of people with HIV receiving Ryan White AIDS Drug Assistance, Outpatient Health services, or Support services, and simulated a loss of suppression in each category if services permanently end or return after delays of 1.5 or 3.5 years. ResultsCessation of Ryan White services in 2025 was projected to result in 69,695 additional infections from 2025-2030 (95% credible interval 18,943 to 123,628) - 68% (18% to 118%) more than if Ryan White were continued. Temporary interruptions of 1.5 and 3.5 years resulted in 26,951 (7,341 to 47,534) and 53,594 (14,645 to 94,860) additional infections, respectively. Excess infections varied across states, from a 45% increase in Texas to 126% in Missouri. ConclusionsProjected increases in HIV infections due to disruptions of Ryan White services threaten the progress made in curtailing the US HIV epidemic, illustrating the critical role Ryan White plays in preventing HIV transmission.

Matching journals

The top 1 journal accounts for 50% of the predicted probability mass.

50% of probability mass above

"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.