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Wastewater Parvovirus B19 Signal Amid Rising Maternal Cases

Clark, J. R.; Tisza, M. J.; Hammerquist, A. L.; Prakash, H.; Munoz, J. L.; Surathu, A.; Javornik Cregeen, S. J.; Parker, N. W.; Sanz Cortes, M.; Hanson, B.; Deegan, J.; Boerwinkle, E.; Barrozo, E. R.; Maresso, A. W.

2025-07-08 epidemiology
10.1101/2025.07.07.25331044 medRxiv
Show abstract

We report widespread detection of parvovirus B19 in Texas Wastewater using hybrid-capture virome sequencing across 43 sites. Wastewater signal correlated with clinical cases at institutional, county, and state levels and preceded case surges by one month. Full-genome coverage enabled real-time mutation tracking, highlighting wastewaters utility for epidemiologic surveillance.

Matching journals

The top 8 journals account for 50% of the predicted probability mass.

1
Water Research
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9.6%
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The Lancet Microbe
○ 44 papers in training set
Top 0.2%
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8
mSystems
● 394 papers in training set
Top 2%
3.4%
50% of probability mass above
9
mSphere
● 302 papers in training set
Top 3%
2.6%
10
Clinical Infectious Diseases
◐ 235 papers in training set
Top 1%
2.4%
11
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Top 0.2%
2.1%
12
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13
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14
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Top 2%
1.7%
15
Proceedings of the National Academy of Sciences
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Top 27%
1.7%
16
Environmental Health Perspectives
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Top 0.2%
1.7%
17
PNAS Nexus
◐ 159 papers in training set
Top 1%
1.7%
18
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Top 1%
1.7%
19
Infection Control & Hospital Epidemiology
◐ 17 papers in training set
Top 0.1%
1.5%
20
Science Translational Medicine
● 127 papers in training set
Top 2%
1.5%
21
Applied and Environmental Microbiology
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Top 4%
1.1%
22
Science Advances
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Top 25%
1.1%
23
mBio
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Top 9%
1.1%
24
Viruses
○ 332 papers in training set
Top 4%
1.0%
25
Emerging Infectious Diseases
● 105 papers in training set
Top 1%
1.0%
26
Cell Reports Medicine
○ 153 papers in training set
Top 5%
0.8%
27
Scientific Reports
○ 3612 papers in training set
Top 73%
0.8%
28
Nature
○ 645 papers in training set
Top 10%
0.8%
29
American Journal of Epidemiology
◐ 67 papers in training set
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30
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"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.