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Lessons learnt from implementing FAIRification workflows in diabetes research in Germany

Inau, E. T.; Dedie, A.; Anastasova, I.; Schick, R.; Frohlich, B.; Roden, M.; Birkenfeld, A. L.; Angelis, M. H. d.; Preusse, M.; Waltemath, D.; Zeleke, A. A.

2025-07-02 health informatics
10.1101/2025.07.01.25330204 medRxiv
Show abstract

The FAIR principles guide data stewardship towards maximizing the value of scientific data while offering a high level of flexibility to accommodate differences in standards and scientific practices. Research communities have developed and implemented domain-specific workflows to make their data FAIR. This work compares the implementation of a structured generic FAIRification workflow with a domain-specific workflow using the example of metadata captured in diabetes research in Germany and applying the FAIR data maturity model developed by the Research Data Alliance. We show that both workflows require similar resources. Interestingly, the implementation of both workflows led us to achieve the same FAIRness rating. We therefore conclude that the adoptions made in the FAIRification workflow for health research data are useful to improve efficiency but do not necessarily lead to higher FAIRness scores when applied to core data sets. Based on the results of our workflow comparison we identified a list of requirements that should be met for the FAIRification of a core data set regardless of the workflow employed. In the future, FAIR data strategies and infrastructure should be planned and implemented as early as possible in the FAIRification journey. It is anticipated that this comparative analysis will help establish standard operating procedures for the FAIRification of core data sets for health studies.

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