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Feasibility of Mini Group Interpersonal psychotherapy (IPT-G mini) for adolescents impacted by COVID-19 in East Africa

Yator, O.; Mwavua, S. M.; Tele, A.; Kathono, J.; Nyongesa, V.; Amin, N.; Kumar, M.

2025-06-16 psychiatry and clinical psychology
10.1101/2025.06.13.25329611 medRxiv
Show abstract

IntroductionGroup Interpersonal Psychotherapy (IPT-G) has universal elements that appeal to non-Western cultural contexts, alongside offering flexibility to make contextual adaptations and making it an intervention of choice for adolescent populations in LMICs. We anticipate that a shorter four-session version, which we are calling IPT-G Mini, offered to adolescents and young people during the COVID-19 pandemic would effectively mitigate psychological distress. Materials and methodsIPT-G mini was offered by lay health workers to 40 adolescents aged 10-19 years in Nairobi, Kenya, experiencing depressive, stress, and anxiety symptoms during the COVID-19 epidemic in June-September 2021. Primary outcomes were a reduction in depression, and psychological distress on the Patient Health Questionnaire (PHQ-9), Revised Childrens Anxiety, and Kessler psychological distress (K10) scales. ResultsThe intervention was effective, with a significant reduction in psychological distress (K-10) and depression (PHQ-9) scores at the end of the intervention (with p<0.05) Cohens d=0.49 (95% C.I. =0.04-0.94) and d=0.51 (95% C.I. = 0.06-0.96) respectively. Younger participants (10-14 years) had better outcomes than older ones on K10 and PHQ-9 assessments. ConclusionIPT-G mini must be tested in a more controlled setting with a larger and more diverse sample. It does appear to reduce distress and depressive symptoms, and further evaluation may be needed to refine the adapted version. Despite the challenges brought by the pandemic, the timely and effective intervention focused on interpersonal issues proved beneficial to participants. Addressing various problem areas helped provide perspective and support in dealing with multiple losses and socioeconomic hardships experienced by our young participants. Trial registryPan African Clinical Trial Registry (pactr.samrc.ac.za) PACTR202501888041900

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