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Quality of life and its determinants among individuals with type 2 diabetes mellitus in rural Bangladesh

Sabin, L.; Kumar Shaha, S.; Kiadaliri, A.; Kuddus, A.; King, C.; Zhou, X.; Ahmed, N.; Jennings, H.; Morrison, J.; Akter, K.; Nahar, T.; Azad, K.; Fottrell, E.; Haghparast-Bidgoli, H.

2025-06-12 health economics
10.1101/2025.06.11.25329444 medRxiv
Show abstract

BackgroundType 2 diabetes mellitus (T2DM) is a growing public health issue in Bangladesh, with the rural population facing significant barriers to diagnosis and care. While previous studies conducted in urban areas have examined the health-related quality of life (HRQoL) of people with diabetes, evidence from rural areas remains limited. MethodsWe analysed data from 1,574 adults with diabetes in rural Bangladesh, from the DMagic cluster randomised trial. HRQoL was assessed using the EQ-5D-3L instrument and the visual analogue scale. HRQoL was compared between people with a previous diagnosis of diabetes and those who were unaware of their condition prior to the study. Multivariable linear regressions and modified Poisson regressions were used to examine the associations between HRQoL and socio-demographic factors, risk behaviours, and comorbidities. ResultsResults indicate that socio-demographic, economic and health factors are associated with HRQoL. The main factors associated with higher HRQoL and clinically relevant were Higher levels of education, being male and belonging to a higher wealth tertile. Individuals with diabetes unaware of their condition were less likely to report problems in mobility, self-care, pain/discomfort and usual activities. ConclusionThe findings emphasised the need for targeted interventions for high-risk groups, especially individuals with low socio-economic levels.

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