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Differential microRNA expression profiling of peripheral blood L1CAM neural-enriched and bulk extracellular vesicles in individuals with bipolar disorder
2025-06-06
psychiatry and clinical psychology
Title + abstract only
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Bipolar disorder (BD) is a common and yet poorly elucidated psychiatric disorder, with emerging evidence implicating a role for epigenetic mechanisms, including microRNAs (miRNAs), in its pathophysiology. These molecules are secreted from cells in extracellular vesicles (EVs), which can be isolated from bodily fluids and tested as potential biomarkers. In individuals with BD and control participants (CON), we characterized the miRNA expression profiles of peripheral blood EVs selected for L1CAM,...
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