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Growth of Paracoccus aminovorans is restricted by L-ascorbic acid (LA) and human gut isolate

Heer, K.; Kayet, P.; Sharma, N.; Basak, S.; Raychaudhuri, S.

2025-06-05 microbiology
10.1101/2025.06.04.657967 bioRxiv
Show abstract

Gut microbiota plays a crucial role in the outcome of cholera. In this context, Paracoccus aminovorans, a gut commensal, has been evidenced to positively influence the pathogenesis of cholera bacterium. In the present study, we examined the impact of various non-antibiotic strategies on the growth of Paracoccus aminovorans. We observed the growth of Paracoccus aminovarans was severely restricted in the presence of L-ascorbic acid as well as in co-culture growth assays with another gut commensal, Weissella confusa.

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