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Disgust-Reduction Evaluative Conditioning (DREC) and tDCS in Contamination-Based OCD: A Randomized Controlled Trial

2025-06-06 psychiatry and clinical psychology Title + abstract only
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BackgroundPeople with contamination-based obsessive-compulsive disorder (C-OCD) experience contamination-related stimuli as more disgusting than normal, which leads to avoidance behavior or washing and cleaning compulsions. This study aimed to investigate whether evaluative conditioning through repetitively pairing a contamination-related stimulus with a pleasant one, and transcranial stimulation over the orbitofrontal cortex (OFC), the brain areas involved in disgust processing, can reduce the ...

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