Back

Obstetric Complications Associated With Adolescent Pregnancy At Livingstone University Teaching Hospital

Chishala, N.; Povia, J. P.; Ngongo, N. N.; Chisanga, J. M.; Mabuku, T.; Yumba, E.; Riwo, E.; Baines, S. M.; Mulambo, P.; Kumeleni, S.; Siame, L.; Mweene, B. C.; Mutengo, K. H.; Siakabanze, C.; Luwaya, E.; Hatwiko, H.; Sichamba, P.; Chakulya, M.; Masenga, S. K.

2025-06-04 obstetrics and gynecology
10.1101/2025.06.01.25328749 medRxiv
Show abstract

BackgroundAdolescent pregnancy remains a major public health concern in sub-Saharan Africa, where limited data exist on region-specific obstetric complications. This study aimed to identify factors associated with maternal morbidity among adolescents at a tertiary referral hospital in Zambia. MethodsA retrospective cross-sectional study was conducted using records of 407 adolescents (10- 19 years) admitted to Livingstone University Teaching Hospital (LUTH) between January 2023 and December 2024. Sociodemographic, clinical, and laboratory variables were evaluated against primary outcomes (preterm labour, preeclampsia/eclampsia, haemorrhage) using multivariable logistic regression. Data were analysed in Statcrunch, with results reported as adjusted odds ratios (AORs) and 95% confidence intervals (CIs). ResultsThe median age was 17 years (IQR 16-18); 90 adolescents (22.1%) experienced [&ge;]1 maternal complication. In multivariable analysis, adverse birth outcomes (preterm delivery or intrauterine death) were associated with 14-fold higher odds of maternal complications (adjusted odds ratio [AOR] 14.3, 95% CI 4.9-42.1; p < 0.0001). Each additional week of gestation was protective (AOR 0.7, 95% CI 0.6-0.8; p < 0.0001). Other factors including age, residence, employment status, parity, foetal complications, and proteinuria were not independently significant. ConclusionsNearly one in five adolescent pregnancies at LUTH is complicated by serious maternal morbidity. Adverse birth outcomes and gestational age emerge as powerful independent predictors. These findings underscore the urgent need for interventions to prevent pre-eclampsia, optimize timing of delivery, and improve perinatal care among adolescents in resource-constrained settings. Prospective, multicentre studies including neonatal outcomes are warranted to guide comprehensive adolescent-focused maternal health strategies.

Matching journals

The top 2 journals account for 50% of the predicted probability mass.

50% of probability mass above

"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.