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Pervasive Intestinal Carriage with Multiple Species of Extended Spectrum Cephalosporin-Resistant Enterobacterales in Children Admitted for Severe Acute Malnutrition at a Tertiary Hospital in Malawi

Holowka, T.; Ashford, A.; Khuu, T.-V.; Bimagambetov, A.; Dial, C. N.; Kondwani, A.; Tepeka, A.-G.; Alby, K.; Juliano, J. J.; Garcia-Pratts, A. J.; Mvalo, T.; Vonasek, B. J.; Ciccone, E. J.; Bartelt, L. A.

2025-05-31 infectious diseases
10.1101/2025.05.30.25328637 medRxiv
Show abstract

Using culture-based screening of stool specimens, 80.3% of 188 children hospitalized for severe acute malnutrition in Malawi carried extended spectrum cephalosporin resistant Enterobacterales (ESCR-E) at admission. 38.3% of children were colonized with multiple ESCR-E species. Over half of the colonized children did not have recent antibiotic exposure or prior hospitalization.

Published in The American Journal of Tropical Medicine and Hygiene (predicted rank #11) · training set

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