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The Neurosurgical Uncertainty Index: Self-Doubting AI for rare or unexpected surgical complications

2025-05-02 surgery Title + abstract only
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Rare or unexpected postoperative neurosurgical complications pose a challenge due to clinical variability and gaps in available data. We introduce the Neurosurgical Uncertainty Index (NUI), an uncertainty-aware AI framework that integrates bootstrap sampling for aleatoric uncertainty, isolation forest anomaly detection, and clinical calibration to predict and stratify risks for 13 complications. NUI distinguishes between data-driven and model-driven uncertainty and highlights cases that conventi...

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