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The effect of COVID-19 and socioeconomic inequalities on emergency department accesses for psychiatric conditions

SCHEPISI, C.; Ventura, M.; Di Napoli, A.; Aragona, M.; Ciampichini, R.; Fano, V.; Napoli, C.; Pacifici, M.; Rosini, C.; Silvestri, C.; Voller, F.; Zucchi, A.; Petrelli, A.

2025-04-28 epidemiology
10.1101/2025.04.25.25326419 medRxiv
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BackgroundCOVID-19 produced a detrimental effect on mental health that could not be appropriately addressed due to a reduced accessibility of healthcare services, as patients with socioeconomic vulnerabilities faced the largest barriers in accessing healthcare during the pandemic. This study aimed to investigate emergency department (ED) accesses with a psychiatric diagnosis before and after COVID-19, with a specific focus on the role of socioeconomic factors. MethodsPopulation-based longitudinal open cohort of residents and NHS beneficiaries aged [≥] 10, was enrolled in three large Italian areas from 1 January 2018 to 31 December 2021 (n=5,159,363). The primary outcome of interest was the first access to an ED (FMHEA); sex, age, deprivation level, citizenship and groups of diagnosis were considered as covariates. Crude incidence rates were calculated comparing the two time periods (pre- and post-COVID-19) by each covariate. In the context of interrupted time series (ITS), incidence rate ratios (IRR) of FMHEAs with 95%CI were estimated via an ITS analysis using a step-change negative binomial model. Temporal trend of FMHEAs was investigated through an ITS analysis on their monthly numbers. ResultsDuring follow-up, 56,762 FMHEAs were observed. The multivariate analysis showed that before COVID-19, the rate of FMHEA was higher among the highly deprived (IRR: 1.28; 95%CI:1.22.-1.35 for highest vs lowest deprivation level), females, people aged [≤]24 and [≥]85 and immigrants. A significant interaction between the COVID-19 period and deprivation level was found: the probability of reduced FMHEA increased with the deprivation level. The greater impact of COVID-19 was found in the central age classes resulting in a reduction in the differences in FMHEA rates by age in the post-Covid-19 period. ConclusionCOVID-19 reduced incidence rates of ED accesses, but increased socioeconomic inequalities in the use of ED for mental health disorders.

Published in PLOS One · not in our set (fewer than 10 published preprints to learn from) · training set

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