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Profiling the human luminal small intestinal microbiome using a novel ingestible medical device
2025-04-20
gastroenterology
Title + abstract only
View on medRxiv
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The invasive nature of sample collection for studying the small intestinal (SI) microbiome often results in its poor characterization. This study evaluated a novel ingestible medical device (MD) for SI luminal sample collection. A monocentric interventional trial (NCT05477069) was conducted on 15 healthy subjects. Metagenomics, metabolomics and culturomics assessed the MDs effectiveness in characterizing the healthy SI microbiome and identifying potential biomarkers. The SI microbiota differed s...
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