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microRNA Biomarkers in Paediatric Infection Diagnostics. Bridging the Gap Between Evidence and Clinical Application: A Scoping Review

2025-04-11 pediatrics Title + abstract only
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ObjectiveThis scoping review aims to assess the evidence regarding miRNA associations with paediatric bacterial and viral infections. IntroductionFebrile children present a challenge in emergency care, often leading to unnecessary antibiotics due to difficulty distinguishing bacterial from viral infections. Current biomarkers lack specificity, contributing to diagnostic uncertainty and antimicrobial resistance. MicroRNAs (miRNAs), detectable in blood and responsive to disease, show promise as i...

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