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Survivorship Navigator: Personalized Survivorship Care Plan Generation using Large Language Models

Pradeepkumar, J.; Pankaj Kumar, S.; Reamer, C. B.; Dreyer, M.; Patel, J.; Liebovitz, D.; Sun, J.

2025-03-28 health informatics
10.1101/2025.03.27.25324782 medRxiv
Show abstract

Cancer survivorship care plans (SCPs) are critical tools for guiding long-term follow-up care of cancer survivors. Yet, their widespread adoption remains hindered by the significant clinician burden and the time- and labor-intensive process of SCP creation. Current practices require clinicians to extract and synthesize treatment summaries from complex patient data, apply relevant survivorship guidelines, and generate a care plan with personalized recommendations, making SCP generation time-consuming. In this study, we systematically explore the potential of large language models (LLMs) for automating SCP generation and introduce Survivorship Navigator, a framework designed to streamline SCP creation and enhance integration with clinical systems. We evaluate our approach through automated assessments and a human expert study, demonstrating that Survivorship Navigator outperforms baseline methods, producing SCPs that are more accurate, guideline-compliant, and actionable.

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