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The missing link: Electronic health record linkage across species offers opportunities for improving One Health

Mullen, K. R.; Saklou, N.; Kiehl, A.; Ong, T. C.; Strecker, G. J.; Toro, S.; VandeWoude, S.; Brooks, I. M.; Webb, T. L.; Haendel, M. A.

2025-03-26 health informatics
10.1101/2025.03.25.25324490 medRxiv
Show abstract

ObjectiveSignificant opportunities for understanding the co-occurrence of conditions across species in coincident households remain untapped. We determined the feasibility of creating a Companion Care Registry (CCR) for analysis of health data from the University of Colorado Health (UCHealth) patients and their companion animals who received veterinary care at the geographically-adjacent Colorado State University Veterinary Teaching Hospital (CSU-VTH). Materials and MethodsUsing a hybrid deterministic and probabilistic record linkage method, non-medical Personally Identifiable Information was securely matched to determine the total number of UCHealth patients within the HIPAA-compliant Health Data Compass Research Data Warehouse (2015-2024) who took a companion animal to the CSU-VTH (2019-2024). Results12,115 matches were identified, indicating 29% of CSU-VTH clients were UCHealth patients. DiscussionThe overlap between CSU-VTH clients and UCHealth patients underscores the potential feasibility and utility of a CCR. ConclusionThis work provides a mechanism to evaluate environmental and inter-species influences on One Health.

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