Anatomy of a Failure: Can a Cognitive-Bias Modification Intervention Improve Physical Activity in Patients Following a Cardiac Rehabilitation Programme?

ObjectivesPromoting regular physical activity (PA) is essential in cardiac rehabilitation; yet many patients exhibit low levels of PA. In January 2022, the Improving Physical Activity (IMPACT) trial, a randomised controlled trial at the University Hospital of Geneva, was launched to promote PA in cardiac patients by targeting automatic approach tendencies towards exercise-related stimuli through a cognitive bias modification (CBM) intervention. This article examines the limited acceptance of this intervention, identifies potential barriers, and proposes strategies to improve future implementations. DesignRetrospective evaluation of a pre-registered clinical trial. SettingThe intervention was conducted in a cardiac rehabilitation centre in Switzerland. Participants. Sixty-eight cardiac rehabilitation patients (Mage = 57.76, SD = 10.76 years, 87% male). InterventionPatients received 12 CBM sessions over 6 weeks, designed to target approach-avoidance tendencies to exercise-related stimuli and improve PA levels. Primary and secondary outcome measuresAcceptance was assessed using behavioural (e.g., enrolment and engagement rates), cognitive (e.g., perceived effectiveness), and emotional (e.g., affective evaluation) indicators. The cognitive and emotional indicators were derived from verbal feedback documented by the research assistants based on patients reactions during the intervention period. These observations do not constitute qualitative research as defined by methodological standards; they were informal notes provided by RAs during intervention delivery and were not collected or analysed using qualitative research methods. ResultsOf the 352 patients initially required, only 68 (19%) were enrolled. Among these 68, 63% completed the minimum number of CBM sessions, and 25% completed accelerometer-based PA measures during the week following discharge. These behavioural indicators of low acceptance showed cognitive (e.g., scepticism about the task relevance and perceived effectiveness of the intervention) and emotional (e.g., feelings of boredom and disinterest) barriers. ConclusionThe low engagement and acceptance observed in the IMPACT trial reveal highlight several key barriers, such as perceived task irrelevance, task monotony, and task boredom, that undermine the acceptance and feasibility of this digital CBM intervention in cardiac rehabilitation. These findings emphasise the importance of designing patient-centred interventions, ensuring their seamless integration into clinical contexts, and conducting qualitative research prior to implementation to anticipate potential barriers. Strengths and limitations of this studyO_LIThis study uses a multidimensional assessment of acceptance by examining behavioural, cognitive, and emotional indicators of a cognitive-bias modification intervention. C_LIO_LIIncluding informal verbal feedback from research assistants (RAs) offer valuable insights into patients experience and perception of the intervention in a real-world cardiac rehabilitation setting. C_LIO_LIAcceptance was assessed primarily through RAs verbal feedback collected during intervention delivery, rather than direct patients reports or standardised measures, which may introduce recall bias and limit the reliability of the findings. C_LI