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Evaluation of Women with Peripartum or Dilated Cardiomyopathy and Their First-Degree Relatives: The DCM Precision Medicine Study

2025-02-21 cardiovascular medicine Title + abstract only
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BackgroundRare variant genetics have been associated with peripartum cardiomyopathy (PPCM) but the role of genetics remains unsettled. ObjectiveThe study sought to compare dilated cardiomyopathy (DCM) genetic risk in first-degree relatives (FDRs) of female patients with DCM or PPCM (probands), and to assess DCM-relevant rare variant prevalence in DCM/PPCM probands and population controls. MethodsClinical and genetic data were analyzed from the DCM Precision Medicine Study. Risk of DCM or parti...

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