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Interplay of Type 2 Inflammation, Small Airway Dysfunction, and Patient-Reported Outcomes in Treatment-Naive Uncontrolled Asthma: A Retrospective Primary Care Analysis

2025-02-25 respiratory medicine Title + abstract only
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BackgroundEffective initial asthma treatment in primary care requires a comprehensive assessment of airway inflammation and lung function impairment, including small airway dysfunction (SAD). We investigated the prevalence of type 2 (T2) inflammation and SAD in treatment-naive patients with uncontrolled asthma who received primary care, and assessed the utility of the Asthma Control Questionnaire-5 (ACQ-5) as a potential indicator of these factors. MethodsThis single-center retrospective study ...

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