Comparative analysis of macrophage feeder systems reveals distinct behaviors and key transcriptional shifts in chronic lymphocytic leukemia cells via coculture
Kohlhas, V.; Jestrabek, H.; Rebollido-Rios, R.; Truong, T. T.; Zoelzer, R.; Schreurs, L. D.; von Lom, A.; vom Stein, A. F.; Hallek, M.; Nguyen, P.-H.
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In this brief report, we evaluated various macrophage coculture systems for their CLL-feeding potential, phagocytosis capacity, induction of treatment resistance in CLL cells, and their impact on the transcriptional profiles of CLL cells.
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