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Severity Of Lung Obstruction And Older Age, But Not Physical Activity, Predict Locomotor Muscle Oxidative Impairment In COPD
2025-01-29
respiratory medicine
Title + abstract only
View on medRxiv
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BackgroundLow muscle oxidative capacity is an extrapulmonary manifestation of chronic obstructive pulmonary disease (COPD) with unclear etiology. We sought to determine clinical and behavioral features associated with muscle oxidative capacity in smokers with and without COPD and never smoker individuals. Methods243 adults enrolled in the Muscle Health Study, an observational study ancillary to COPDGene. Gastrocnemius oxidative capacity was measured by near-infrared spectroscopy from muscle oxy...
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