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Hepatitis B core related antigen (HBcrAg) point of care tests as a risk stratification tool: experience from Kenya

Downs, L. O.; Okanda, D.; Chirro, O.; Zaharani, M.; Safari, B.; Aliyan, N.; Andersson, M. I.; Tanaka, Y.; Etyang, A. O.; Shimakawa, Y.; Githinji, G.; Matthews, P. C.

2024-11-26 infectious diseases
10.1101/2024.11.25.24316890 medRxiv
Show abstract

We undertook a point-of-care test (POCT) for hepatitis B core-related antigen (HBcrAg) on adults living with HBV in Kilifi, Kenya. A positive test identified all with hepatitis B viral load >200,000 IU/ml, who were HBeAg positive, and correlated with higher ALT (p = 0.03), raised APRI (p<0.001) and elastography scores (p = 0.03).

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