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Influence of acute myocardial ischemia on arrhythmogenesis: a computational study
2024-11-22
cardiovascular medicine
Title + abstract only
View on medRxiv
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AO_SCPLOWBSTRACTC_SCPLOWThe early phase of acute myocardial ischemia is associated with an elevated risk of ventricular reentrant arrhythmias. Indeed, after partial or total occlusion of a coronary artery, some regions of the heart experience a reduction in myocardial blood flow. This causes metabolic and cellular processes, such as hypoxia, hyperkalemia and acidosis, which lead to changes in the transmembrane ionic dynamics. The effect of such alterations may result in the formation of electric...
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