Back

Multi-omic analyses of a twin pair with mirror image cleft lip identifies pathogenic variant in FGF20 modified by differential methylation upstream of ZFP57

2024-11-18 genetic and genomic medicine Title + abstract only
View on medRxiv
Show abstract

BackgroundDisturbances in the intricate processes that control craniofacial morphogenesis can result in birth defects, most common of which are orofacial clefts (OFCs). Nonsyndromic cleft lip (nsCL), one of the phenotypic forms amongst OFCs, has a non-random laterality presentation with the left side being affected twice as often compared to the right side. This study investigates the etiology of nsCL and the factors contributing to its laterality using a pair of monozygotic twins with mirror-im...

Predicted journal destinations

1
The American Journal of Human Genetics
77 training papers
Top 0.6% 14.2%
2
Genetics in Medicine
57 training papers
Top 1% 8.8%
3
Human Genetics and Genomics Advances
39 training papers
#1 8.8%
4
Nature Communications
483 training papers
Top 13% 7.6%
5
Nature Genetics
72 training papers
Top 2% 6.3%
6
Scientific Reports
701 training papers
Top 48% 5.8%
7
PLOS Genetics
39 training papers
Top 0.6% 4.1%
8
Genome Medicine
56 training papers
Top 3% 4.1%
9
Human Molecular Genetics
28 training papers
Top 0.4% 3.8%
10
Journal of Medical Genetics
22 training papers
Top 0.2% 3.8%
11
Genes
21 training papers
Top 0.4% 1.9%
12
Frontiers in Genetics
32 training papers
Top 1% 1.9%
13
European Journal of Human Genetics
25 training papers
Top 2% 1.9%
14
Cell Genomics
34 training papers
Top 3% 1.9%
15
npj Genomic Medicine
18 training papers
Top 0.9% 1.5%
16
iScience
74 training papers
Top 5% 1.5%
17
eLife
262 training papers
Top 30% 1.5%
18
PLOS ONE
1737 training papers
Top 95% 1.5%
19
Proceedings of the National Academy of Sciences
100 training papers
Top 11% 1.3%
20
Nature
58 training papers
Top 6% 1.1%
21
Brain
69 training papers
Top 10% 0.9%
22
Translational Psychiatry
94 training papers
Top 9% 0.9%
23
International Journal of Molecular Sciences
39 training papers
Top 5% 0.9%
24
Journal of Clinical Medicine
77 training papers
Top 24% 0.7%
25
Communications Biology
36 training papers
Top 6% 0.7%
26
Bioinformatics
24 training papers
Top 4% 0.7%