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Imaging Infants and Children with Investigational Handheld Optical Coherence Tomography with Widefield Lens: A Pilot Study

Li, A. S.; Imperio, R.; Tran-Viet, D.; Mangalesh, S.; Prakalapakorn, S. G.; Vajzovic, L.; Maldonado, R.; Freedman, S. F.; Chen, X.

2024-11-04 ophthalmology
10.1101/2024.10.30.24316132 medRxiv
Show abstract

Handheld optical coherence tomography (OCT) systems have shown promises to provide detailed evaluation of the pediatric retina. It is less stressful for preterm infants compared to binocular indirect ophthalmoscopy and shows promises for screening for retinopathy of prematurity. There are currently only one commercially available non-contact handheld OCT systems, and no commercially available widefield handheld OCT systems. Here we report and evaluate the first use of the Theia Imaging Investigational handheld OCT system with widefield lens (T1-W, Theia Imaging, Durham, NC) in pediatric subjects. We compare the OCT en face view to handheld widefield or tabletop ultra-widefield fundus photographs and evaluate the ability to visualize the vitreoretinal interface, intraretinal, subretinal and choroidal features on cross-sectional OCT scans.

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