NIAGADS: A Comprehensive National Data Repository for Alzheimer's Disease and Related Dementia Genetics and Genomics Research
Kuzma, A.; Valladares, O.; Greenfest-Allen, E.; Nicaretta, H.; Kirsh, M.; Ren, Y.; Katanic, Z.; White, H.; Wilk, A.; Bass, L.; Brettschneider, J.; Carter, L.; Cifello, J.; Chuang, W.-H.; Clark, K.; Gangadharan, P.; Haut, J.; Ho, P.-C.; Horng, W.; Iqbal, T.; Jin, Y.; Keskinen, P.; Lerro Rose, A.; Moon, M. K.; Manuel, J.; Qu, L.; Robbins, F.; Saravanan, N.; Sha, J.; Tate, S.; Zhao, Y.; Cantwell, L.; Gardner, J.; Chou, S.-Y.; Tzeng, J.-Y.; Bush, W.; Naj, A.; Kuksa, P.; Lee, W.-P.; Leung, Y. Y.; Schellenberg, G.; Wang, L.-S.
Show abstract
NIAGADS is the National Institute on Aging (NIA) designated national data repository for human genetics research on Alzheimers Disease and related dementia (ADRD). NIAGADS maintains a high-quality data collection for ADRD genetic/genomic research and supports genetics data production and analysis. NIAGADS hosts whole genome and exome sequence data from the Alzheimers Disease Sequencing Project (ADSP) and other genotype/phenotype data, encompassing 209,000 samples. NIAGADS shares these data with hundreds of research groups around the world via the Data Sharing Service, a FISMA moderate compliant cloud- based platform that fully supports the NIH Genome Data Sharing Policy. NIAGADS Open Access consists of multiple knowledge bases with genome-wide association summary statistics and rich annotations on the biological significance of genetic variants and genes across the human genome. NIAGADS stands as a keystone in promoting collaborations to advance the understanding and treatment of Alzheimers disease.
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