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A browser-based platform for storage, visualization, and analysis of large-scale 3D images in HPC environments

Walker, L. A.; Lee, W. J.; Duan, B.; Weatherspoon, M.; Li, Y.; Shen, F. Y.; Cheng, M.-C.; Niu, X.; Eggerd, J.; Xie, B.; Cheng, J. H. P.; Xu, H.; Zhong, X.-X.; Jiang, H.; Cui, M.; Yan, Y.; Cai, D.

2024-10-04 bioinformatics
10.1101/2024.10.04.616591 bioRxiv
Show abstract

High-throughput microscopy necessitates 3D image storage, visualization, and analysis in terabyte to petabyte scales. Centralized high-performance computing (HPC) infrastructure provides the resources, but interfacing software is limited. We developed an extensible platform with a scalable image storage format (SISF) and content delivery network (CDN) to enable fast, random access to compressed data. Additionally, we built a cloud-based nTracer2 software to annotate neuron morphology from SISF images in a web browser.

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