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Prognostic value of an integrated human papilloma virus and immunoscore model to predict survival in vulva squamous cell carcinoma
2024-09-12
oncology
Title + abstract only
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BackgroundWhile the prognostic value of immune-related biomarkers is well characterized in many solid tumors, their significance in vulva squamous cell carcinoma (VSCC) remains unclear. Here, we report a comprehensive analysis of programmed death-ligand 1 (PD-L1) and immune cell infiltrates in VSCC and establish immunoscore models for classification of the disease. MethodsArchival tissues, immunohistochemistry, and digital quantification were used to investigate the number of CD4+, CD8+, CD68+,...
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