The patient voice: valproate, topiramate and MHRA regulation
Hanna, J.; Waddams, F.; Jones, S. L.; Arkell, R.; Angus-Leppan, H.
Show abstract
Valproate and topiramate use are increasingly restricted by government regulations, such as those of the MHRA. The views of people with epilepsy and their families affected by these have been little studied. This qualitative study examines 19 people with epilepsy and their views on the restrictions, and examines the thematic outcomes of these views - in terms of direct damage of avoiding valproate or topiramate (including SUDEP), missed opportunities and disruption of belief systems. Recommendations to align the regulations to human rights and true informed decision making are made.
Matching journals
The top 5 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Childhood trauma in patients with epileptic versus non-epileptic seizures 93%
- Can artificial intelligence diagnose seizures based on patients' descriptions? A study of GPT-4 92%
- Development of an Antiseizure Drug Screening Platform for Dravet Syndrome at the NINDS contract site for the Epilepsy Therapy Screening Program 92%
Similar papers in this journal
- Lived experiences of caregivers of persons with epilepsy attending an epilepsy clinic at a tertiary hospital, eastern Uganda: A phenomenological approach 94%
- An international study to investigate and optimise the safety of discontinuing valproate in young men and women with epilepsy: protocol 93%
- The use of carbogen for interruption of febrile seizures - the randomized controlled CARDIF trial 92%
Similar papers in this journal
- The Global Epilepsy Needs Study (GENS): A mixed-methods, multi-country exploration of the unmet psychosocial and everyday needs of people with epilepsy 95%
- A disease concept model for STXBP1 -related disorders 93%
- Frequency of and factors associated with antiseizure medication discontinuation discussions and decisions in patients with epilepsy: a multicenter retrospective chart review 93%
Similar papers in this journal
- Attributional bias in epilepsy: differences between genetic generalised epilepsy, temporal lobe epilepsy and healthy controls 91%
- Chemically-induced epileptic seizures in zebrafish: a systematic review 90%
- Distinct psychopathology profiles in patients with epileptic seizures compared to non-epileptic psychogenic seizures 90%
Similar papers in this journal
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.