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Analysis of a Stochastic COVID-19 and Hepatitis B Coinfection Model with Brownian and Levy Noise

POBBI, M. A.; MOORE, S. E.; NAANDAM, S. M.

2024-08-12 epidemiology
10.1101/2024.08.12.24311861 medRxiv
Show abstract

In this article, we formulate and analyse a mathematical model for the co-infection of Hepatitis B virus and COVID-19. We incorporate into our framework Hepatitis B virus prevention, COVID-19 prevention, COVID-19 vaccination, and environmental factors so as to investigate their effect on transmission dynamics. First, we derive the basic reproduction number for HBV only, COVID-19 only, and co-infection stochastic models using the next generation matrix method. Next, we establish the conditions for stability in the stochastic sense for HBV only, COVID-19 only sub-models, and the co-infection model. Furthermore, we devote our attention to finding sufficient conditions for extinction and persistence. Finally, by using the Euler-Murayama scheme, we illustrate the dynamics of the co-infection, COVID-19, HBV and the effect of some parameters on disease transmission dynamics by means of numerical simulations.

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