Metformin reduces the risk of poor treatment outcomes among individuals with rifampicin-resistant tuberculosis and type-2 diabetes mellitus
Salindri, A. D.; Gujabidze, M.; Kipiani, M.; Lomtadze, N.; Tukvadze, N.; Avaliani, Z.; Blumberg, H. M.; Kornfeld, H.; Kempker, R. R.; Magee, M. J.
10.1101/2024.07.12.24310348 medRxivShow abstract
We conducted a retrospective cohort study among individuals with rifampicin-resistant tuberculosis and diabetes to determine the association between metformin use and tuberculosis treatment outcomes. We found that individuals with metformin use had a significantly lower risk of poor tuberculosis treatment outcomes (adjusted RR=0.25, 95%CI 0.06 - 0.95) compared to those without.
Matching journals
The top 3 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Potential Utility of C-reactive Protein for Tuberculosis Risk Stratification among Patients with Non-Meningitic Symptoms at HIV Diagnosis in Low- and Middle-Income Countries 95%
- Understanding non-adherence to tuberculosis medications in India using urine drug metabolite testing: a cohort study 95%
- C-reactive protein for pulmonary tuberculosis screening and treatment response monitoring in children 94%
Similar papers in this journal
- Effect of the COVID-19 pandemic on drug-resistant tuberculosis treatment outcomes at a national referral hospital in Sierra Leone, 2017 to 2022: a retrospective study 94%
- Accuracy of digital chest x-ray analysis with artificial intelligence software as a triage and screening tool in hospitalized patients being evaluated for tuberculosis in Lima, Peru 94%
- Evaluating the health impact, health-system costs and cost-effectiveness of using TrueNat on stool samples compared to usual care for the diagnosis of paediatric tuberculosis in primary care settings: a modelling analysis 93%
Similar papers in this journal
- Sex differences in TB treatment outcomes: Retrospective cohort study and meta-analysis 95%
- Stool processing methods for Xpert Ultra testing in childhood tuberculosis: A prospective, multi-country accuracy study 92%
- Comparative effectiveness of three linezolid management strategies for peripheral neuropathy during multidrug- or rifampicin-resistant tuberculosis treatment 92%
Similar papers in this journal
Similar papers in this journal
- Adherence trajectory as an on-treatment risk indicator among drug-resistant TB patients in the Philippines 94%
- The monocyte-to-lymphocyte ratio: defining a normal range, sex-specific differences in the tuberculosis disease spectrum and diagnostic indices 94%
- Treatment for radiographically active, sputum culture-negative pulmonary tuberculosis: a systematic review and meta-analysis 94%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.