Clinical Utility of the Molecular Microscope Diagnostic System in a Real-World Transplant Cohort: Moving Towards a New Paradigm

2024-06-26 transplantation Title + abstract only

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ObjectivesTo evaluate the clinical implications of adjunctive molecular gene expression analysis (MMDx) of biopsy specimens in heart transplant (HT) recipients with suspected rejection. IntroductionHistopathological evaluation remains the standard method for rejection diagnosis in HT. However, the wide interobserver variability combined with a relatively common incidence of "biopsy-negative" rejection has raised concerns about the likelihood of false-negative results. MMDx, which uses gene expr...

Clinical Utility of the Molecular Microscope Diagnostic System in a Real-World Transplant Cohort: Moving Towards a New Paradigm

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