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Candidate Genes from an FDA-Approved Algorithm Fail to Predict Opioid Use Disorder Risk in Over 450,000 Veterans
2024-05-16
addiction medicine
Title + abstract only
View on medRxiv
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ImportanceRecently, the Food and Drug Administration gave pre-marketing approval to algorithm based on its purported ability to identify genetic risk for opioid use disorder. However, the clinical utility of the candidate genes comprising the algorithm has not been independently demonstrated. ObjectiveTo assess the utility of 15 variants in candidate genes from an algorithm intended to predict opioid use disorder risk. DesignThis case-control study examined the association of 15 candidate gene...
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