Emergence Of Oxa-48-Like Carbapenemases In Clinical Enterobacterales From Guatemala
Mazariegos, C. J.; Quinto, A.; Herrera, A.; Barillas, S. E.; Valenzuela, L. R.; Ordonez, G.; Sierra, P.; Arevalo, C.; Seah, C.; Melano, R. G.
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Five isolates (four Klebsiella pneumoniae and one Escherichia coli) displaying resistance to piperacillin/tazobactam and ertapenem and reduced susceptibility to imipenem were found positive for blaOXA-48-like genes (blaOXA-181 and blaOXA-232) carried on plasmids described previously. Although two K. pneumoniae recovered in 2020 were clonally related, the results suggest that blaOXA-48-like genes have been circulating in Guatemala since 2019. This is the first report of this type of carbapenemase in Central America.
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