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Epigenetic Mechanisms Regulating the Association between OR2L13 and Major Psychiatric Disorders

2024-03-04 psychiatry and clinical psychology Title + abstract only
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BackgroundPreviously, population-based cohort studies have identified the association between epigenetic modifications of OR2L13 related to mental disorders and Gestational diabetes mellitus (GDM). However, the causal nature of these associations remains difficult to establish owing to confounding. AimsThe purpose of the study was to investigate the causal effect of methylation of OR2L13 and offspring mental health outcomes. MethodWe performed two-sample mendelian randomisation to assess the e...

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